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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2849f871c6cca0ddb4033daf12510a01607f30b15d001141c5b7294839cecfd' 
  AND token = 'Y+/bpzRGpRRiXQI6FpNicJvvRPVej6Aihbi2OF5o8oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}