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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6462e5d562462c6dc1b0fe77de8641624c9fbc9e8ecd51927f25575be747e6f2' 
  AND token = 'U/wB4HO36fjUycRDtuhaZqPPBhEwiO9M7i5SOr6pI/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}