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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b46a5721d47f7e9b09ed0ec38732d3a8872226cf0026b66e11a33fed91efe0' 
  AND token = 'taInnRS6xM8fFwyP3gOXTSsOfQOxHkEVoRsALnEuxg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}