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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7c837a8819f67980f89cf9feb07c74306a29c2b4627d42dda9f2adf43e0f4b' 
  AND token = 'mZG1DT52T4u4k2Pz/kMGVE4F9fQCaZmWfKkjUkzVvog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}