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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50c6038da292bf0aa9ca684c33563cac2369fa0c126a06b30e70343c34c049f6' 
  AND token = 'z1NKBG+i4yYiN8li9B5KmW849/Yvz4Hos5NqK++pxjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}