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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea0823cd21149296c59805c44d55fb0fca51ce9d266406b2fd76d90203df2201' 
  AND token = 'ktU6eNZ6GLkMzPQu+xriGLKNoLYULghyW/id2+y9s5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}