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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7080f8e59df76007476b4dd0965bb09693ee839ab06eb7d32f1eef91634ed426' 
  AND token = '69QeS8M22Hc/vmnOOgQS0oQcipNUILNKelKRaw3D2Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}