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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc2943ae98ee6f7426d4178317788602a01f7816901354c3932b4353313b4c4f' 
  AND token = 'fELDWcKjUhONdE0IAjiEkU2qbyTQsrBQVBUEgPyJzy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}