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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f065dfd8afaf71ed73926d6b6add3201f82f7e236374ed26b62490a880d4d6b' 
  AND token = 'QFNvmlgxEkaQI02/1BI6e+Bk4D1FjjkWo1C8Euy5aY4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}