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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5765783584493ec68cf4de24088a06bc1e562650b28e59260b97f4ea14e41a2' 
  AND token = 'THMGC1f/D6EW8zlXCxWO+2WFJDCdSqMU1h7oaCNdHAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}