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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '940243765412ec09ebd0b9aef6ae8239ab582e9b2adbc9de42257e4eaa3debac' 
  AND token = '1XMdFgkdOVAf6E1a8SyU3avxfCPgniV190jsEmuI1n0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}