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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67a3ab8780cbd2c6b7ad4609fd0eb8713fd12de30fe2f2912f796f802de0e152' 
  AND token = 'zsyLdfINqkMEFRJ++Pl6yE9A5lB6nPE2Imw8lq7S6+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}