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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a6c506636a3d9f99a8015f88bfdd3fbc86be1ff882d308954d7a51fbc290009' 
  AND token = 'wGAoNRnwYYzS0vgsJoS6oxMArtDPVYRXD3FMA/fXxB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}