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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca1c44368a2bae2a60cacb856bcaef6684f5d48385cbd9ff9673a79e326a219' 
  AND token = 'eLzQyFBc+CLyMAkHvzs7RqtWw4e563jvscDsvkAT3/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}