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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7228e6de78231afddb83967157f7742ea670b9b844a037b59f80e9b4b3940799' 
  AND token = 'Gpugb+ObXlm2Xe5w8C9XC2ztnHiL5KoR94wt9ScGlcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}