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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e4f961c19bc39019e1539e20d70ec2945228a68c59227addc50ad16a5a644ff' 
  AND token = '6s8u+Ktm8ptO8HXffE4FK3ao2gQ2eURlWNVL5UUXwfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}