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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35242c7b9682a5693c406013c1bbd9f924ab5f9134cf95a896e082890375e7bf' 
  AND token = 'WF5CcGkXFE3CP0jAiYx7P8m+g1wUgSFwe02NIg3Syn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}