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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1dc6035c803a02006628fb4ab2152ca515e91b148dc9f4bb994a50f175e7183' 
  AND token = 'HXdC2W10i3pyj+KPkLCr1VX4B0l6Br0qGpUxQ8QbeoM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}