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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dc387e13871c18649e47c768ec258c3e043f90a986eafb252f6bbeb237b4b52' 
  AND token = '3oYsZuXdWpETGT/Uy3C7lo6IEYHJ6wQD26CnNqZrRNU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}