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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2582897ef6e2bf663b8dc458e5fb6ff95023d93b7ea4b5ff46204dc3c82fff68' 
  AND token = 'ZK/qR+/ixuB6vlQb5OsiwU/s+ae2pM0ms4qYSB0TC3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}