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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '294a989914eedf53e07168172fcb1e1dfa20870e8df5e6f6ef257b3282883b6a' 
  AND token = 'HeGjiwBDLieH29CtHRe7K8Rgv5+C336u35brxcC8qB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}