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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c2063272b6f5bdbc0c1d98c3e616cefbf884e1e5be8de2b6530e1f6c451d020' 
  AND token = '22gJN3ldBpFzjCOEFdPVgYVLiosE9CEfUCxD/ClY3aU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}