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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d056540e7212ae8a39be425efb1902be58db3307e637b05de2d6aed1e4cd8e5' 
  AND token = '33sMW/Bs/sCaY4w436MtnjmqlKBDq3bn0Ml5Z0lVWdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}