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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '206c43160ebaf0247cf9beff2c93df721bdeca5e3919ca8e41a19e3ab9c5014b' 
  AND token = 'ynIy4Aui0/CV8sc4w1mgCEdHVzV+UdVIw6pfgrCi8qQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}