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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22791f0c51ac457508ad4171f2204af8b81177e8216e442b517d844f056292a9' 
  AND token = 'rSVbBvK78QbcdZlrYwn9QcQ7aHQENLX0hUT+aSFKuEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}