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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '492bbe9e51ca186e8444c9a16e66d9a76a02f4dc18ec52f27d6da29249e2b0cc' 
  AND token = 'joiaFXcTr1zgDd3sbT4DwiCY3FKCvo85IrFqVK2Y2zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}