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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5eeaf3c9647c93274b79375b8aae7c36bc9b0588f95b5503db2d54390e8d5f69' 
  AND token = 'a2E/9tFNWto8PR5q0i0JoaOuSMHB2gyMHggD8BEFfUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}