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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5454e6708a3e1758d2b6d744c4425c051cca1321600f75ee27a6f7cabdca74da' 
  AND token = 'wnFoJuWcz+8gSYGofJWiGo2oPxn4tbPhO1HmfR4js+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}