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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24dd15502ca79ee18a055de918987b2f4e6a6b8f294a80c95717984b43798f14' 
  AND token = 'ya00G7d6ZndKlbIjS5ss1TputhS6nr3OEDqJMc8CI4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}