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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c99b2311f43601da663eff40f058953c2e72e03b66301a6af7424b1db49d65c6' 
  AND token = 'thysHA4brD1vMuT1MuAHe/c704UXOx4bbU75zfzUL/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}