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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dff3cb3fdbe80be2a1c44e103d3b058acacf56a0bd0c7539f49f91b1fb410cf1' 
  AND token = 'S+kMO3MyTEw3JYRX2uhabKSt70vu0C7R788+RcyD1zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}