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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4fbc0c22f915d9e0a51364f5332703637ed1650483bb1f5c244f88bbec31142' 
  AND token = 'Xi25atOWB802fhsYvROOehL7vMmrRvKsoHfvsEhs9yY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}