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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0142b39a51660529131b0c2f6aeb5b30ab6b733c9e50bdb6a1d6b2f9a75d4641' 
  AND token = 'IUH1kLxcbje2Uy2eqna5io5jQJrjOEjjQQjt7TP3r/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}