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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be143d4910508a5008e5464e695a8d207298f5e896508c6577764b6610b30d4a' 
  AND token = '0AkyNRbUr5wi+aywo7f3bx3Z7qRacIXYCqBTXRlYWWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}