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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca9515f196a88861f71eec5be1b738a3b56e80a07edd464d42936905ee4b0e50' 
  AND token = 'T6Gi775B1MppHoMTsvsiVgmQs/0kt0nwUFvvN2mwjWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}