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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '491b8a094b122ff1baa212f4ef2d25412d4fbc614710f5732a632bcb4fc0e68b' 
  AND token = 'PIkT8VMebflOJxNjw6UAjPqUQLa5u/ntcL1WjmKJgP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}