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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9339cf4f168ad6d8be6005fe99f3378e6c5566f58d5bf964260c3a89dc91c269' 
  AND token = '4/eRlDL0mKWG5Fgzle1cXX6TXdVhTCIaOFAcyKBvtp0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}