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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82f9cadbd4a02d332728f35030041d6649222383fe960d71f93e95aa5296ca4b' 
  AND token = 'e/4NcbU7RB0y2AvDfC+VvVDFcMmYO7UTLGjozoPso18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}