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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '288a4f3ddc877ba37042f8f7c30351abfe17f690cd9bd18be24bcf32f20a1ae5' 
  AND token = 'vcKZqSJLF0mpz4+v1df6P/m9NeEcqKjkosGL1NC6t4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}