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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '457329cb8cdd7f4b3f4dc86e3e41fd98f09a3ab3dc4157d3f02ab7968043597e' 
  AND token = 'xCmtI/f2Lq9JfvaJOHt2x0qXuk8Ei6h9j+JRtJowQso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}