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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '290c6f1ceb9895066a81b449e00edc3e5ce7ddcacb042bb55927c46344749216' 
  AND token = 'o6Pi/G5HDWmCFSZQIucLKz4UcXESQeI3LDcY9u3aWv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}