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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53f6dad37ac3e6e6e85b796d2f34dc4c2e34878272a4ea0f5d6743e454e477e' 
  AND token = '+giAJr2l8qqNWSjX+xgTwQkXCsj7U98ZDjmchu26L1o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}