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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c2568b6d5e643ee654f8fa711f8635301e78f7792bd3f95b2af9728c6c2d0c6' 
  AND token = '8PU6ttLogC0ldB7uIZNuso0nImm/AzwfdeUHjMvNw1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}