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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b8da482aad78844fd0459297fa14d9c2219ed6976d6716b4026407e83040ed' 
  AND token = 'kQDGQwUmzc6uOKHFsZvTP+YPvs9k9r9x4ni2eWHFkhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}