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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65f0ab59361059778260b54d38d75e528068ceed12f579b38a6ae2212699a33' 
  AND token = 'zxH1IO98w4m1BSPOL+PX5yWm/zr6lgZEC2bW3U4ifjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}