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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef689c769941978506d4c465bff1a953dd75e7b38363f2694747ea2dc5a33aa' 
  AND token = 'EI14LqsZyA11GtTL8VSrapGxug8dJ9xqr7d43FXavMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}