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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c033ca49cddc0939cfa905dde9ad69e8905ce8b83ba6fb9a6073375931fd5483' 
  AND token = 'pp1islrw1AlMMG9Mm8Vk4I/fLy7oXlb2RjfCaYxR3YM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}