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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46249c422a20a2c7904e4575e8f5ad17bf4331efeb898600ad673463223c7769' 
  AND token = 'a7rO1T5cjRc/hIgC43fMO8sTKqE0RwEopr5cnQs2EBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}