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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074a0445eca2c7c74c86f67df8d35d4a297f47055c3cb5f438966455f3b83908' 
  AND token = 'lF7z64CRBeGVRWCB+wbk1z+YFq157lrafc4JVrxzNPQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}