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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9291d5b264c526a226dccf1494aa5dd23907d6878baf66bec81466187c649622' 
  AND token = 'fnJb7wTH8WZDdDDCb9+i4JtD0NuldC8y/5mRFGPusCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}